Research Projects

Riddell Centre investigators are advancing cancer treatment by developing innovative cell and immune therapies. Learn more about the cutting-edge methods and research projects driving these breakthroughs forward.

Project	Cancer type(s)	Keywords
Exploring how gut bacteria impact the effectiveness of CAR T-cell cancer therapy Principal Investigator: Kathy McCoy Co-Investigators: Robert Puckrin, Sorana Morrissy, Douglas Mahoney, Mona Shafey	Blood cancers	CAR T cell therapy, preclinical models, microbiome
Precision CAR T Cell Therapy for Glioblastoma: Developing Safe, Multi-Targeted Treatments with Logic-Gated CAR T Cells Principal Investigator: Franz Zemp Co-Investigators: Sorana Morrissy, Douglas Mahoney, Jennifer Chan, Snow Guo	Glioblastoma	CAR T cell therapy
Improving CAR T Therapy with Gene Editing Technologies Principal Investigator: Pierre Billon Co-Investigator: Lou Baudrier, Douglas Mahoney, Nicolas Jacquelot	Cancer agnostic	CAR T cell therapy, CRISPR gene editing, preclinical models

Project

Cancer type(s)

Keywords

Exploring how gut bacteria impact the effectiveness of CAR T-cell cancer therapy

Principal Investigator: Kathy McCoy
Co-Investigators: Robert Puckrin, Sorana Morrissy, Douglas Mahoney, Mona Shafey

Blood cancers

CAR T cell therapy, preclinical models, microbiome

Precision CAR T Cell Therapy for Glioblastoma: Developing Safe, Multi-Targeted Treatments with Logic-Gated CAR T Cells

Principal Investigator: Franz Zemp
Co-Investigators: Sorana Morrissy, Douglas Mahoney, Jennifer Chan, Snow Guo

Glioblastoma

CAR T cell therapy

Improving CAR T Therapy with Gene Editing Technologies

Principal Investigator: Pierre Billon
Co-Investigator: Lou Baudrier, Douglas Mahoney, Nicolas Jacquelot

Cancer agnostic

CAR T cell therapy, CRISPR gene editing, preclinical models